CAPRIN1 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human CAPRIN1 wild-type allele is located in the vicinity of 11p13 and is approximately 51 kb in length. This allele, which encodes caprin-1 protein, plays a role in RNA binding and the formation of cytoplasmic ribonucleoprotein granules, which downregulate protein translation. Mutation of the gene is associated with both childhood-onset neurodegeneration with cerebellar ataxia and cognitive decline (CONDCAC), and neurodevelopmental disorder with language impairment, autism and attention deficit-hyperactivity disorder (NEDLAAD).

**Synonyms:** - CONDCAC - Caprin 1 Gene - Cell Cycle Associated Protein 1 wt Allele - GPI-Anchored Membrane Protein, 137-kD Gene - GPIAP1 - GPIP137 - GRIP137 - M11S1 - Membrane Component, Chromosome 11, Surface Marker 1 Gene - NEDLAAD - RNG105 - p137GPI