TLC ELL-12

**Semantic type:** Organic Chemical|Pharmacologic Substance

**Definition:** A liposomal formulation of the ether lipid 1-O-octadecyl-2-O-methyl-sn-glycero-3-phosphocholine with potential antineoplastic activity. TLC ELL-12 induces tumor cell apoptosis via mitochondria- and caspase-mediated mechanisms. Liposomal encapsulation reduces the free agent's hemolytic toxicity. (NCI04)

**Synonyms:** - 1-0-Octadecyl-2-O-methyl-Sn-3-glycero-phosphocholine Liposome - ELL-12