Immunoglobulin Heavy Chain Component

**Semantic type:** Immunologic Factor

**Definition:** A protein sequence that is a component of immunoglobulin heavy (IGH) chains. IGH chain proteins are encoded by several families of genes those encoding isotype-specific constant regions (IGHA1, IGHA2, IGHD, IGHE, IGHG1, IGHG2, IGHG3, IGHG4 and IGHM) and three families encoding the antigen binding regions, including the heavy variable, diversity and joining (V-(D)-J) genes (IGHV subgroups 1-8; IGHD subgroups 1-7 and IGHJ subgroups 1-6).

**Synonyms:** - IGH Component