Amphicrine Carcinoma

**Semantic type:** Neoplastic Process

**Definition:** A carcinoma that shows both neuroendocrine and non-neuroendocrine differentiation in the same malignant cells. It has been described in the digestive system and extra-digestive sites. It is distinct from mixed neuroendocrine non-neuroendocrine neoplasms as it does not contain two distinct neoplastic components, one neuroendocrine and one non-neuroendocrine.