Severe Junctional Epidermolysis Bullosa 3B

**Semantic type:** Disease or Syndrome

**Definition:** An autosomal recessive condition caused by mutation(s) in the LAMC2 gene, encoding laminin subunit gamma-2. It is characterized by severe skin blisters and erosions and is often fatal.

**Synonyms:** - Generalized Severe Epidermolysis Bullosa - JEB-H - JEB3B - Junctional Epidermolysis Bullosa Type Herlitz