Allogeneic Anti-CD20 CAR T Cells LUCAR-20SP

**Semantic type:** Cell|Pharmacologic Substance

**Definition:** A preparation of donor-derived T-lymphocytes that have been genetically modified to express a chimeric antigen receptor (CAR) targeting the tumor-associated antigen (TAA) cluster of differentiation 20 (CD20), with potential immunostimulating and antineoplastic activities. Upon administration, allogeneic anti-CD20 CAR T-cells LUCAR-20SP specifically recognize and kill CD20-expressing tumor cells. CD20, a non-glycosylated cell surface phosphoprotein, is a B-cell specific cell surface antigen expressed in B-cell lineage malignancies.

**Synonyms:** - Allogeneic Anti-CD20 CAR T-cells LUCAR-20SP - Allogeneic Anti-CD20 CAR-T Cells LUCAR-20SP - LUCAR 20SP - LUCAR-20SP - LUCAR20SP