KMT2A/CREBBP Fusion Protein

**Semantic type:** Amino Acid, Peptide, or Protein

**Definition:** A fusion protein encoded by the KMT2A/CREBBP fusion gene. This protein is comprised of the N-terminus from histone-lysine N-methyltransferase 2A (containing the AT-hooks and transcriptional repression domain) fused to the C-terminus of CREB-binding protein (including the CREB binding domain, bromodomain, histone acetyltransferase domain).

**Synonyms:** - Histone-Lysine N-Methyltransferase 2A/CREB-Binding Protein Fusion Protein - Histone-Lysine N-Methyltransferase 2A::CREB-Binding Protein Fusion Protein - KMT2A-CREBBP Fusion Protein - KMT2A::CREBBP Fusion Protein - MLL-CBP Fusion Protein - MLL-CREBBP Fusion Protein - MLL/CBP Fusion Protein - MLL/CREBBP Fusion Protein