KMT2A/FOXO3 Fusion Protein

**Semantic type:** Gene or Genome

**Definition:** A fusion protein encoded by the KMT2A/FOXO3 fusion gene. This protein is comprised of the N-terminus from histone-lysine N-methyltransferase 2A (containing the AT-hooks and one zinc finger domain) fused to the C-terminus of epidermal forkhead box protein O3 (excluding the forkhead domain and including the transactivation domain, which contains both the nuclear localization sequence and nuclear export domain).

**Synonyms:** - Histone-Lysine N-Methyltransferase 2A/Forkhead Box Protein O3 Fusion Protein - Histone-Lysine N-Methyltransferase 2A::Forkhead Box Protein O3 Fusion Protein - KMT2A-FOXO3 Fusion Protein - KMT2A::FOXO3 Fusion Protein - MLL-FKHRL1 Fusion Protein - MLL-FOXO3 Fusion Protein - MLL/FKHRL1 Fusion Protein - MLL/FOXO3 Fusion Protein