Neuroendocrine-Specific Protein

**Semantic type:** Amino Acid, Peptide, or Protein

**Definition:** Three different proteins encoded by the RTN1 gene. They are identical at their 3-prime ends but have unique amino termini. The common carboxyl-terminal region contains 2 large hydrophobic domains. The proteins are localized to membranes of the endoplasmic reticulum, leading to their proposed designation as 'reticulons.' Their function is largely unknown. (from OMIM)

**Synonyms:** - NSP - RTN1 - Reticulon 1