TNXB wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human TNXB wild-type allele is located within 6p21.33-p21.32 and is approximately 74 kb in length. This allele, which encodes tenascin-X protein, is involved in the negative regulation of cell migration and the promotion of collagen fibril formation. Mutations in the gene are associated with classic-like Ehlers-Danlos syndrome 1 and vesicoureteral reflux 8.

**Synonyms:** - EDS3 - EDSCLL - EDSCLL1 - Growth-Inhibiting Protein 45 Gene - HXBL - Hexabrachion-Like Gene - TENX - TN-X - TNX - TNXB1 - TNXB2 - TNXBS - Tenascin X Gene - Tenascin XB wt Allele - Tenascin XB1 Gene - Tenascin XB2 Gene - VUR8 - XB - XBS