UCP2 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human UCP2 wild-type allele is located in the vicinity of 11q13.4 and is approximately 9 kb in length. This allele, which encodes dicarboxylate carrier SLC25A8 protein, plays a role in the regulation of glucose metabolism by the Krebs cycle. Mutations in the gene are associated with body mass index quantitative trait 4 (BMIQ4)-related susceptibility to obesity.

**Synonyms:** - BMIQ4 - Body Mass Index QTL 4 Gene - Body Mass Index Quantitative Trait 4 Gene - SLC25A8 - UCPH - Uncoupling Protein 2 (Mitochondrial, Proton Carrier) Gene - Uncoupling Protein 2 wt Allele