Activating FLT1 Gene Mutation

**Semantic type:** Cell or Molecular Dysfunction

**Definition:** A change in the nucleotide sequence of the FLT1 gene that results in constitutive activation of vascular endothelial growth factor receptor 1 protein and its downstream signaling pathways.

**Synonyms:** - Activating FLT Gene Mutation - Activating FLT-1 Gene Mutation - Activating FRT Gene Mutation - Activating Fms Related Tyrosine Kinase 1 Gene Mutation - Activating VEGFR-1 Gene Mutation - Activating VEGFR1 Gene Mutation - Activating Vascular Endothelial Growth Factor Receptor 1 Gene Mutation - FLT1 Activating Gene Mutation - FLT1 Activating Mutation