Activating FLT4 Gene Mutation

**Semantic type:** Cell or Molecular Dysfunction

**Definition:** A change in the nucleotide sequence of the FLT4 gene that results in constitutive activation of vascular endothelial growth factor receptor 3 protein and its downstream signaling pathways.

**Synonyms:** - Activating FMS Related Tyrosine Kinase 4 Gene Mutation - Activating PCL Gene Mutation - Activating VEGFR-3 Gene Mutation - Activating VEGFR3 Gene Mutation - Activating VGR3 Gene Mutation - Activating Vascular Endothelial Growth Factor Receptor 3 Gene Mutation - FLT4 Activating Gene Mutation - FLT4 Activating Mutation