Activating NTRK2 Gene Mutation

**Semantic type:** Cell or Molecular Dysfunction

**Definition:** A change in the nucleotide sequence of the NTRK2 gene that results in constitutive activation of BDNF/NT-3 growth factors receptor protein and its downstream signaling pathways.

**Synonyms:** - Activating Neurotrophic Tyrosine Kinase Receptor 2 Gene Mutation - Activating Neurotrophic Tyrosine Kinase Receptor Type 2 Gene Mutation - Activating TRKB Gene Mutation - Activating TRKB Tyrosine Kinase Gene Mutation - Activating Tropomyosin-Related Kinase B Gene Mutation - NTRK2 Activating Gene Mutation - NTRK2 Activating Mutation