MEGF8 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human MEGF8 wild-type allele is located in the vicinity of 19q13.2 and is approximately 53 kb in length. This allele, which encodes multiple epidermal growth factor-like domains protein 8, is involved in the downregulation of the hedgehog signaling pathway. Mutations in the gene are associated with Carpenter syndrome 2.

**Synonyms:** - C19orf49 - CRPT2 - Chromosome 19 Open Reading Frame 49 Gene - EGF-Like Domain-Containing Protein 4 Gene - EGF-Like-Domain, Multiple 4 Gene - EGFL4 - Epidermal Growth Factor-Like 4 Gene - FLJ22365 - HBV Pre S2 Binding Protein 1 Gene - HBV Pre-S2 Binding Protein 1 Gene - HBV Pre-S2-Binding Protein 1 Gene - Hepatitis B Virus Pre-S2-Binding Protein 1 Gene - KIAA0817 - Multiple EGF Like Domains 8 wt Allele - Multiple EGF-Like-Domains 8 Gene - SBP1