UROS wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human UROS wild-type allele is located in the vicinity of 10q26.2 and is approximately 38 kb in length. This allele, which encodes uroporphyrinogen-III synthase protein, is involved in the synthesis of the porphyrin precursor uroporphyrinogen III. Mutations in the gene are associated with congenital erythropoietic porphyria.

**Synonyms:** - Congenital Erythropoietic Porphyria Gene - Hydroxymethylbilane Hydrolyase Gene - UROIIIS - Uroporphyrinogen III Decarboxylase Gene - Uroporphyrinogen III Synthase wt Allele