WDR45 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human WDR45 wild-type allele is located in the vicinity of Xp11.23 and is approximately 27 kb in length. This allele, which encodes WD repeat domain phosphoinositide-interacting protein 4, is involved in phosphoinositide binding and autophagy. Mutations in the gene are associated with neurodegeneration with brain iron accumulation 5.

**Synonyms:** - JM5 - NBIA4 - NBIA5 - Neurodegeneration with Brain Iron Accumulation 5 Gene - WD Repeat Domain 45 wt Allele - WD Repeat Domain, X-Linked 1 Gene - WD45 Repeat Protein Interacting with Phosphoinositides 4 Gene - WDRX1 - WDRXI4 - WIPI-4 - WIPI4