Major Salivary Gland Adamantinoma-Like Ewing Sarcoma

**Semantic type:** Neoplastic Process

**Definition:** An exceedingly rare variant of Ewing sarcoma with epithelial differentiation that resembles carcinoma and arises from the major salivary glands. Morphologically, it is characterized by the presence of nests of basaloid cells, tumor cell palisading, myxoid or hyalinized stroma, focal keratin pearl formation, and high-grade features with minimal pleomorphism.

**Synonyms:** - Major Salivary Gland ALES - Salivary Gland ALES - Salivary Gland Adamantinoma-Like Ewing Sarcoma