Autologous Anti-CD19 CAR T-cells GLPG5101

**Semantic type:** Cell|Pharmacologic Substance

**Definition:** A preparation of autologous stem-like early memory T-lymphocytes that have been genetically engineered to express a chimeric antigen receptor (CAR) specific for the tumor-associated antigen (TAA) CD19, with potential immunomodulating and antineoplastic activities. Upon administration, autologous anti-CD19 CAR T-cells GLPG5101 specifically recognize and kill tumor cells expressing CD19. CD19 antigen is a B-cell specific cell surface antigen expressed in all B-cell lineage malignancies.

**Synonyms:** - 19CP 02 - 19CP-02 - 19CP02 - Autologous Anti-CD19 CAR T Cells GLPG5101 - Autologous Anti-CD19 CAR-T Cells GLPG5101 - GLPG 5101 - GLPG-5101 - GLPG5101