ADH5 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human ADH5 wild-type allele is located in the vicinity of 4q23 and is approximately 18 kb in length. This allele, which encodes alcohol dehydrogenase class-3 protein, is involved in the oxidation of the formaldehyde adduct S-(hydroxymethyl) glutathione and in the metabolism of long-chain primary alcohols and long chain omega-hydroxy fatty acids. Mutations in the gene are associated with digenic AMED syndrome.

**Synonyms:** - ADH, Class III Gene - ADH-3 - ADHX - AMEDS - Alcohol Dehydrogenase 5 (Class III), Chi Polypeptide wt Allele - Alcohol Dehydrogenase 5, Chi Polypeptide Gene - Alcohol Dehydrogenase, Chi Isozyme Gene - BMFS7 - Epididymis Secretory Sperm Binding Protein Li 60p Gene - FALDH - FDH - Formaldehyde Dehydrogenase Gene - Formaldehyde Dehydrogenase, Glutathione-Dependent Gene - GSH-FDH - GSNOR - HEL-S-60p - S-Nitrosoglutathione Reductase Gene