AGXT wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human AGXT wild-type allele is located in the vicinity of 2q37.3 and is approximately 12 kb in length. This allele, which encodes alanine-glyoxylate aminotransferase protein, is involved in gluconeogenesis, L-serine metabolism and glyoxylate detoxification. Mutations in the gene are associated with primary hyperoxaluria 1.

**Synonyms:** - AGT - AGT1 - AGXT1 - Alanine--Glyoxylate Aminotransferase Gene - Alanine--Glyoxylate and Serine--Pyruvate Aminotransferase Gene - Alanine-Glyoxylate Aminotransferase wt Allele - Glycolicaciduria Gene - Hepatic Peroxisomal Alanine:Glyoxylate Aminotransferase Gene - L-Alanine: Glyoxylate Aminotransferase 1 Gene - Oxalosis I Gene - PH1 - Primary Hyperoxaluria Type 1 Gene - SPAT - SPT - Ser-PyrAT - Serine:Pyruvate Aminotransferase Gene - TLH6