ALDH5A1 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human ALDH5A1 wild-type allele is located in the vicinity of 6p22.3 and is approximately 42 kb in length. This allele, which encodes succinate-semialdehyde dehydrogenase, mitochondrial protein, plays a role in the metabolism of glutamate, succinate and gamma-aminobutyric acid (GABA). Mutations in the gene are associated with succinic semialdehyde dehydrogenase deficiency.

**Synonyms:** - Aldehyde Dehydrogenase 5 Family Member A1 wt Allele - Aldehyde Dehydrogenase 5 Family, Member A1 Gene - Mitochondrial Succinate Semialdehyde Dehydrogenase Gene - SSADH - SSDH - Succinate-Semialdehyde Dehydrogenase Gene - Succinic Semialdehyde Dehydrogenase, NAD(+)-Dependent Gene