Autologous Anti-CD83 CAR T-cells

**Semantic type:** Cell|Pharmacologic Substance

**Definition:** A preparation of autologous T-lymphocytes engineered to express a chimeric antigen receptor (CAR) targeting CD83, with potential antineoplastic activity. Upon administration, autologous anti-CD83 CAR T-cells recognize and kill CD83-expressing tumor cells. CD83 is expressed on acute myeloid leukemia (AML) blasts.

**Synonyms:** - Autologous Anti-CD83 CAR T Cells - Autologous Anti-CD83 CAR-T Cells