KRAS Mutant Inhibitor KQB365

**Semantic type:** Pharmacologic Substance

**Definition:** An inhibitor of one or more KRAS mutations, with potential antineoplastic activity. Upon administration, KRAS mutant inhibitor KQB365 targets, binds to and inhibits one or more KRAS mutations, thereby inhibiting KRAS mutant-dependent signaling. This inhibits the proliferation of and induces apoptosis in tumor cells in which KRAS is mutated. KRAS plays an important role in cell signaling, division and differentiation. Mutations of KRAS may induce constitutive signal transduction leading to tumor cell growth, proliferation, invasion, and metastasis.

**Synonyms:** - KQB 365 - KQB-365 - KQB365 - KRAS Inhibitor KQB365