Phosphorylated Serine-Protein Kinase ATM

**Semantic type:** Amino Acid, Peptide, or Protein

**Definition:** A post-translationally modified form of serine-protein kinase ATM where one or more serine or threonine residues are phosphorylated. DNA-damage stimulates phosphorylation and autophosphorylation of serine residues in this protein and activates its kinase activity, which promotes DNA repair and cell cycle checkpoint signaling.

**Synonyms:** - Phospho-ATM - Phosphorylated ATM - Phosphorylated ATM Serine/Threonine Protein Kinase - Phosphorylated Ataxia Telangiectasia Mutated Protein - Phosphorylated Ataxia Telangiectasia Protein - p-ATM - pATM