TRAPPC4 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human TRAPPC4 wild-type allele is located 11q23.3 and is approximately 7 kb in length. This allele, which encodes trafficking protein particle complex subunit 4 protein, is involved in the regulation of Rab1 GTPase activity, autophagy and endoplasmic reticulum to Golgi transport. Mutations in the gene are associated with neurodevelopmental disorder with epilepsy, spasticity, and brain atrophy.

**Synonyms:** - CGI-104 - HSPC172 - NEDESBA - PTD009 - SBDN - SYNBINDIN - TRS23 - TRS23 Homolog Gene - Trafficking Protein Particle Complex 4 Gene - Trafficking Protein Particle Complex Subunit 4 wt Allele - Trafficking Protein Particle Complex, Subunit 4 Gene