MAGEL2 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human MAGEL2 wild-type allele is located in the vicinity of 15q11.2 and is approximately 4 kb in length. This allele, which encodes MAGE-like protein 2, plays a role in the regulation of ubiquitin-protein transferase activity, endosomal protein recycling and circadian rhythm. Mutations in the gene are associated with Schaaf-Yang syndrome and may be associated with Prader-Willi syndrome.

**Synonyms:** - MAGE Family Member L2 wt Allele - MAGE-Like 2 Gene - Melanoma Antigen Family L2 Gene - NDNL1 - Necdin-Like 1 Gene - PWLS - SHFYNG - nM15