AP1S2 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human AP1S2 wild-type allele is located in the vicinity of Xp22.2 and is approximately 29 kb in length. This allele, which encodes AP-1 complex subunit sigma-2 protein, plays a role in recruitment of clathrin and cargo proteins to the membrane of the Golgi apparatus. Mutations in the gene are associated with Pettigrew syndrome.

**Synonyms:** - Adapter-Related Protein Complex 1 Sigma-1B Subunit Gene - Adaptor Protein Complex AP-1 Sigma-1B Subunit Gene - Adaptor Related Protein Complex 1 Sigma 2 Subunit Gene - Adaptor Related Protein Complex 1 Subunit Sigma 2 wt Allele - Adaptor-Related Protein Complex 1, Sigma-2 Subunit Gene - Clathrin Adaptor Complex AP1 Sigma 1B Subunit Gene - Clathrin Adaptor Complex AP1, Sigma-1B Subunit Gene - Clathrin-Associated/Assembly/Adaptor Protein, Small 1-Like Gene - DC22 - MRX59 - MRXS21 - MRXS5 - MRXSF - Mental Retardation, X-Linked 59 Gene - Mental Retardation, X-Linked, Syndromic 5 Gene - PGS - Pettigrew X-Linked Mental Retardation Syndrome Gene - SIGMA1B