CPAP wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human CPAP wild-type allele is located within 13q12.12-q12.13 and is approximately 52 kb in length. This allele, which encodes centrosomal P4.1-associated protein, plays a role in microtubule dynamics, centrosome maintenance and centriole duplication. Mutations in the gene are associated with Seckel syndrome 4 and autosomal recessive primary microcephaly 6.

**Synonyms:** - BM032 - CENP-J - CENPJ - Centromeric Protein J Gene - Centrosome Assembly and Centriole Elongation Protein wt Allele - LAP - LIP1 - LYST-Interacting Protein LIP1 Gene - MCPH6 - Microcephaly, Primary Autosomal Recessive 6 Gene - SASS4 - SCKL4 - Sas-4 - Seckel Syndrome 4 Gene - Spindle Assembly Abnormal 4 Gene