CEP152 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human CEP152 wild-type allele is located in the vicinity of 15q21.1 and is approximately 98 kb in length. This allele, which encodes centrosomal protein of 152 kDa, is involved in the regulation of serine/threonine-protein kinase PLK4-localization and cilium biogenesis and degradation. Mutations in the gene are associated with Seckel syndrome 5 and autosomal recessive primary microcephaly 9.

**Synonyms:** - Asterless Gene - Centrosomal Protein 152 wt Allele - Centrosomal Protein 152kDa Gene - Centrosomal Protein, 125-kD Gene - KIAA0912 - MCPH4 - MCPH9 - Microcephaly, Primary Autosomal Recessive 9 Gene - SCKL5