D2HGDH wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human D2HGDH wild-type allele is located in the vicinity of 2q37.3 and is approximately 34 kb in length. This allele, which encodes D-2-hydroxyglutarate dehydrogenase, mitochondrial protein, is involved in the oxidation of D-2-hydroxyglutarate, D-malate and D-lactate. Mutations in the gene are associated with D-2-hydroxyglutaric aciduria.

**Synonyms:** - D-2-Hydroxyglutarate Dehydrogenase wt Allele - D2HGD - FLJ42195 - MGC25181