FECH wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human FECH wild-type allele is located in the vicinity of 18q21.31 and is approximately 42 kb in length. This allele, which encodes ferrochelatase, mitochondrial protein, is involved in the final step in the heme biosynthetic pathway. Mutations in the gene are associated with erythropoietic protoporphyria.

**Synonyms:** - EPP - EPP1 - FCE - Ferrochelatase (Protoporphyria) Gene - Ferrochelatase wt Allele - Heme Synthase Gene - Heme Synthetase Gene - Iron Chelatase Gene - Protoporphyria Gene