GATAD2B wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human GATAD2B wild-type allele is located in the vicinity of 1q21.3 and is approximately 134 kb in length. This allele, which encodes transcriptional repressor p66-beta protein, plays a role in transcriptional repression via regulation of nucleosome deacetylation. Mutations in the gene are associated with autosomal dominant mental retardation 18 (GAND syndrome).

**Synonyms:** - GANDS - GATA Zinc Finger Domain Containing 2B wt Allele - KIAA1150 - MRD18 - Transcription Repressor p66 Beta Component of the MeCP1 Complex Gene - p66 - p66-Beta - p66beta - p68