PDX Development and Trial Centers Research Network

**Semantic type:** Professional or Occupational Group

**Definition:** A network of patient-derived xenograft (PDX) laboratory research units and a PDX coordinating center originally funded by the Cancer Moonshot program. It coordinates collaborative, large-scale development and pre-clinical testing of targeted therapeutic agents in patient-derived models to advance the vision of cancer precision medicine, develops new PDX models and methods for preclinical testing of single agents and drug combinations, and conducts studies of response of PDX models to novel therapeutic strategies using the newly established models, as well as other existing well-characterized PDX models.

**Synonyms:** - PDXNet - PDXNet