t(1;3)(p36.3;q21.3)

**Semantic type:** Cell or Molecular Dysfunction

**Definition:** A chromosomal translocation involving breakpoints within the p36.3 band on the short arm of chromosome 1 and the q21.3 band on the long arm of chromosome 3. This rearrangement may be associated with RPN1-PRDM16 fusion gene expression and various myeloproliferative disorders and leukemias.