GDAP1 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human GDAP1 wild-type allele is located in the vicinity of 8q21.11 and is approximately 197 kb in length. This allele, which encodes ganglioside-induced differentiation-associated protein 1, plays a role in the regulation of mitochondrial fission and fusion. Mutations in the gene are associated with several types of Charcot-Marie-Tooth disease, including axonal type 2K, type 4A, axonal type with vocal cord paresis and recessive intermediate type A.

**Synonyms:** - CMT2K - CMT4 - CMT4A - CMTRIA - Charcot-Marie-Tooth Neuropathy 4A Gene - Ganglioside Induced Differentiation Associated Protein 1 wt Allele