GNS wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human GNS wild-type allele is located in the vicinity of 12q14.3 and is approximately 46 kb in length. This allele, which encodes N-acetylglucosamine-6-sulfatase protein, is involved in glycosaminoglycan degradation. Mutations in the gene are associated with mucopolysaccharidosis type IIID (Sanfilippo D).

**Synonyms:** - G6S - Glucosamine (N-Acetyl)-6-Sulfatase wt Allele - Sanfilippo Disease IIID Gene