HGD wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human HGD wild-type allele is located in the vicinity of 3q13.33 and is approximately 54 kb in length. This allele, which encodes homogentisate 1,2-dioxygenase protein, is involved in phenylalanine and tyrosine catabolism. Mutations in the gene are associated with alkaptonuria.

**Synonyms:** - AKU - HGO - Homogentisate 1,2-Dioxygenase (Homogentisate Oxidase) Gene - Homogentisate 1,2-Dioxygenase wt Allele - Homogentisate Oxidase Gene