Hydroxymethylglutaryl-CoA Lyase, Mitochondrial

**Semantic type:** Amino Acid, Peptide, or Protein|Enzyme

**Definition:** Hydroxymethylglutaryl-CoA lyase, mitochondrial (325 aa, ~34 kDa) is encoded by the human HMGCL gene. This protein is involved in the cleavage of hydroxymethylglutaryl-CoA to yield acetoacetic acid and acetyl-CoA.

**Synonyms:** - 3-Hydroxy-3-Methylglutarate-CoA Lyase - 3-Hydroxy-3-Methylglutaryl-CoA Lyase - EC 4.1.3.4 - HL - HMG-CoA Lyase - HMGCL - Hydroxymethylglutaryl-CoA Lyase - Hydroxymethylglutaryl-Coenzyme A Lyase, Mitochondrial - Mitochondrial 3-Hydroxy-3-Methylglutaryl-CoA Lyase