HOGA1 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human HOGA1 wild-type allele is located in the vicinity of 10q24.2 and is approximately 28 kb in length. This allele, which encodes 4-hydroxy-2-oxoglutarate aldolase, mitochondrial protein, is involved in the metabolism of hydroxyproline, glyoxylate and pyruvate. Mutations in the gene are associated with primary hyperoxaluria type III.

**Synonyms:** - 4-Hydroxy-2-Oxoglutarate Aldolase 1 wt Allele - C10orf65 - Chromosome 10 Open Reading Frame 65 Gene - DHDPS2 - DHDPSL - Dihydrodipicolinate Synthase-Like, Mitochondrial Gene - Dihydrodipicolinate Synthetase Homolog 2 (E. coli) Gene - Dihydrodipicolinate Synthetase Homolog Gene - FLJ37472 - HP3 - N-Acetylneuraminate Pyruvate Lyase 2 (Putative) Gene - NPL2 - Probable 4-Hydroxy-2-Oxoglutarate Aldolase, Mitochondrial Gene