L2HGDH wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human L2HGDH wild-type allele is located in the vicinity of 14q21.3 and is approximately 75 kb in length. This allele, which encodes L-2-hydroxyglutarate dehydrogenase, mitochondrial protein, is involved in the production of 2-oxoglutarate. Mutations in the gene are associated with L-2-hydroxyglutaric aciduria.

**Synonyms:** - 2-Hydroxyglutarate Dehydrogenase Gene - Alpha-Hydroxyglutarate Oxidoreductase Gene - Alpha-Ketoglutarate Reductase Gene - C14orf160 - Chromosome 14 Open Reading Frame 160 Gene - FLJ12618 - FLJ42195 - L-2-Hydroxyglutarate Dehydrogenase wt Allele - L-Alpha-Hydroxyglutarate Dehydrogenase Gene - L2HGA