L-2-Hydroxyglutarate Dehydrogenase, Mitochondrial

**Semantic type:** Amino Acid, Peptide, or Protein|Enzyme

**Definition:** L-2-hydroxyglutarate dehydrogenase, mitochondrial (463 aa, ~50 kDa) is encoded by the human L2HGDH gene. This protein plays a role in the oxidation of L-2-hydroxyglutarate yielding 2-oxoglutarate (alpha-ketoglutarate).

**Synonyms:** - 2-Hydroxyglutarate Dehydrogenase - Alpha-Hydroxyglutarate Oxidoreductase - Alpha-Ketoglutarate Reductase - Duranin - EC 1.1.99.2 - L-2-Hydroxyglutarate Dehydrogenase - L-Alpha-Hydroxyglutarate Dehydrogenase - L2HGDH