Activating IDH1 Gene Mutation

**Semantic type:** Cell or Molecular Dysfunction

**Definition:** A change in the nucleotide sequence of the IDH1 gene that results in aberrant activation of the isocitrate dehydrogenase [NADP] cytoplasmic protein.

**Synonyms:** - Activating IDH1 Mutation - Activating Isocitrate Dehydrogenase (NADP(+)) 1, Cytosolic Gene Mutation - Activating Isocitrate Dehydrogenase 1 (NADP+), Soluble Gene Mutation - Gain of Function IDH1 Gene Mutation - Gain of Function IDH1 Mutation - IDH1 Activating Mutation - IDH1 Gain of Function Gene Mutation - IDH1 Gain of Function Mutation - IDH1 Gene Activating Mutation