Activating IDH2 Gene Mutation

**Semantic type:** Cell or Molecular Dysfunction

**Definition:** A change in the nucleotide sequence of the IDH2 gene that results in aberrant activation of the isocitrate dehydrogenase [NADP], mitochondrial protein.

**Synonyms:** - Activating IDH2 Mutation - Activating Isocitrate Dehydrogenase (NADP(+)) 2, Mitochondrial Gene Mutation - Activating Isocitrate Dehydrogenase 2 (NADP+), Mitochondrial Gene Mutation - Gain of Function IDH2 Gene Mutation - Gain of Function IDH2 Mutation - IDH2 Activating Mutation - IDH2 Gain of Function Gene Mutation - IDH2 Gain of Function Mutation - IDH2 Gene Activating Mutation