Hereditary Gastric and Breast Cancer Syndrome

**Semantic type:** Disease or Syndrome

**Definition:** An autosomal dominant cancer predisposition syndrome caused by mutation in CDH1 or CTNNA1 genes. It is characterized by the development of diffuse gastric carcinoma and/or lobular breast carcinoma.

**Synonyms:** - DGLBC - Diffuse Gastric and Lobular Breast Cancer Syndrome - HGBCS