Sodium Borocaptate

**Semantic type:** Inorganic Chemical|Pharmacologic Substance

**Definition:** A boron-carrying compound. After parenteral administration, sodium borocaptate accumulates preferentially in tumor cells. When exposed to neutron irradiation, borocaptate absorbs neutrons and self-destructs releasing short-range alpha radiation and 'recoil' lithium in tumor cells, resulting in alpha radiation-induced tumor cell death. This highly selective, localized radiotargeting of tumor cells, known as boron neutron capture therapy (BNCT), spares adjacent normal tissues. (NCI04)

**Synonyms:** - BSH - BSH - Borocaptate Sodium - Borocarpin - sodium borocaptate