MAPK8IP3 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human MAPK8IP3 wild-type allele is located in the vicinity of 16p13.3 and is approximately 64 kb in length. This allele, which encodes C-Jun-amino-terminal kinase-interacting protein 3, plays a role in the modulation of Jun kinase signaling, which regulates axon development and anterograde axonal protein transport. Mutations in the gene are associated with neurodevelopmental disorder with or without variable brain abnormalities (NEDBA).

**Synonyms:** - C-Jun-Amino-Terminal Kinase Interacting Protein 3 Gene - Homolog of Drosophila Sunday Driver 2 Gene - JIP-3 - JIP3 - JSAP1 - KIAA1066 - Mitogen-Activated Protein Kinase 8 Interacting Protein 3 wt Allele - NEDBA - SYD2 - Sunday Driver Drosophila Homolog of 2 Gene - Sunday Driver, Drosophila, Homolog of, 2 Gene - syd