MASTL wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human MASTL wild-type allele is located in the vicinity of 10p12.1 and is approximately 33 kb in length. This allele, which encodes serine/threonine-protein kinase greatwall protein, is involved in cellular entry to and progression of mitosis. Mutations in the gene may be associated with thrombocytopenia-2, aplastic anemia or abnormal megakaryocytopoiesis.

**Synonyms:** - FLJ14813 - GREATWALL - GW - GWL - Greatwall Kinase Homolog Gene - Greatwall Protein Kinase Gene - MAST-L - Microtubule Associated Serine/Threonine Kinase Like wt Allele - Microtubule Associated Serine/Threonine Kinase-Like Gene - THC2