MMP12 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human MMP12 wild-type allele is located in the vicinity of 11q22.2 and is approximately 12 kb in length. This allele, which encodes macrophage metalloelastase protein, is involved in extracellular matrix protein proteolysis and wound healing. Mutations in the gene may be associated with chronic obstructive pulmonary disease (COPD).

**Synonyms:** - HME - ME - MME - MMP-12 - Macrophage Elastase Gene - Matrix Metallopeptidase 12 (Macrophage Elastase) Gene - Matrix Metallopeptidase 12 wt Allele - Matrix Metalloproteinase 12 (Macrophage Elastase) Gene