MPI wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human MPI wild-type allele is located in the vicinity of 15q24.1 and is approximately 12 kb in length. This allele, which encodes mannose-6-phosphate isomerase protein, plays a role in the metabolism of D-mannose. Mutations in the gene are associated with congenital disorder of glycosylation 1B.

**Synonyms:** - CDG1B - Mannose Phosphate Isomerase wt Allele - Mannosephosphate Isomerase Gene - PMI - PMI1 - Phosphomannose Isomerase 1 Gene